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Professional research paper about chlamydia

Medicine/ Chlamydia term paper 16207

Today, Sexually Transmitted Diseases ( STD 's ) , are among the most common causes of unwellness in the United States. Peoples in their teens and mid-twentiess are most affected by STD¹s, with over 6 million new instances each twelvemonth, and grownups between the ages of 13 and 19 are at the most hazard for infection. Chlamydia is the most common bacterial sexually familial disease in the United States today. It is estimated that more than 4 million new instances occur each twelvemonth in people of all ages, the bulk of which is in immature grownups. 1 Many STD¹s are present in today¹s society, and people are holding sex with the outlook that it could ne'er go on to them. This is non the instance at all. Particularly with STD¹s like Chlamydia. This peculiar disease is rapidly distributing through the state due to it¹s uncommon happening of symptoms. Peoples are distributing it around without even cognizing that they have it. Chlamydia is at an even greater hazard in the Santa Clara County, where it is the figure one STD among sexually active people in our area.2 Chlamydia is caused by the bacteriums Chlamydia trachomatis. This bacterium can merely populate interior of cells, therefore it can merely be passed on through the exchange of bodily fluids such as seeds, blood, chest milk, and vaginal fluids. It can be transmitted during vaginal, unwritten, or anal sexual contact with an septic spouse. Chlamydia can be treated because it is a bacterial infection. If intervention is non prescribed in clip, nevertheless, the disease most frequently consequences in sterility in both work forces and adult females.

This infection occurs chiefly in the urethra in work forces. Work force are the primary bearers. The symptoms, if present, include things like painful, firing esthesiss with micturition, frequent micturition, and unusual discharge of fluids from the phallus. Many times, nevertheless, Chlamydia goes unnoticed because of a deficiency of symptoms. The disease can be tested for with a laboratory sample of the cells within the tissue of the urethra. The idea of this trial entirely is adequate to deter many a adult male from traveling into a clinic and acquiring checked. This and the female trial uses a procedure called DNA elaboration to observe the cistrons of the beings in venereal secernments. Recently, the U.S. Food and Drug Administration approved this procedure for sensing of Chlamydia in piss. This is a major measure in naming Chlamydia because it does non necessitate a tissue sample ; it can be used in state of affairss where executing a pelvic test isn¹t possible, like in college wellness units and at wellness carnivals. Consequences from the urine trial are available within 24 hours, another added motivation factor to acquire tested in the attempts to control the rise of this STD. Untreated Chlamydia will do epidiymitis, an redness of a portion of the male generative system located near the testiss, hurting and puffiness in the scrotum, marking and obstruction in the urethra and vessel defrens, and if left untreated long plenty, asepsis. It can do proctitis, or an inflamed rectum, and pinkeye, or an redness of the liner of the oculus, as well.3 The bacterium besides have been found in the pharynx as a consequence of unwritten sexual contact with an septic spouse.

Chlamydia in adult females occurs in the neck. Womans are more likely to non see any symptoms, therefore the disease frequently goes untreated. Symptoms that are present may include things like vaginal discharge, hurting in the pelvic country, and shed blooding between periods. These early symptoms are most frequently mild, but do come on into terrible phases. Chlamydia is tested for in adult females with something similar to a pablum vilification, in other words, a sample of the cells run alonging the neck is scraped off with a little tool, so it is less intimidating than the male version of the same trial. If left untreated the adult female may see an unusual discharge and light shed blooding between periods, this hemorrhage may bespeak the spread of infection to the uterus.4 PID, a mark of untreated Chlamydia that occurs in one tierce of all adult females infected, can ensue in scarring of the fallopian tubing, which can barricade the tubing and prevent fertilisation from taking topographic point. Around 100,000 adult females each twelvemonth become sterile as a consequence of PID. In other instances, marking may interfere with the transition of the fertilized egg down into the womb. When this happens, the egg may engraft in the fallopian tubing. This is called ectopic or tubal gestation. This is dangerous for the female parent and consequences in the loss of the fetus.5 A babe who is exposed to Chlamydia in the birth canal during bringing may develop pinkeye, which is an oculus infection, or pneumonia. Symptoms of pinkeye, which include discharge and conceited palpebras, normally develop within the first 10 yearss of life. Symptoms of pneumonia, including a strong cough and congestion, most frequently develop within three to six hebdomads of birth. Both conditions can be treated successfully with antibiotics.

Doctors normally prescribe antibiotics such as a one-day class of Zithromax or a weeklong class of Vibramycin to handle Chlamydial infections. Other antibiotics such as Erythrocin or ofloxacin besides are effectual. Pregnant adult females can be treated with Zithromax or Erythrocin. Amoxicillin is besides a safe option for handling pregnant adult females. Penicillin, which is frequently used for handling some other STD 's, is non effectual against Chlamydial infections.6 New medicines are being developed that should simplify intervention and assist command the spread of Chlamydia from female parent to pamper every bit good as through sexual intercourse. Because of these hazards and hazards to the newborn, many physicians recommend everyday testing of all pregnant adult females for a Chlamydial infection.

Chlamydia

Chlamydia Sexually transmitted diseases infect 1000000s of people a twelvemonth. Some of the commonly known sexually transmitted diseases are herpes, syphillis, HIV, AIDS, venereal warts, and gonorrhoea. Some of these diseases are fatal, others can be cured with antibiotics. All of these are unsafe, but the most common sexually familial disease is a disease that isn & apos ; t as good known. This disease is called chlamydia. Chlamydia is a disease that is infecting immature grownups all over the state. This disease is of great concern for persons in high school and those in college. This disease is the taking cause of asepsis. Chlamydia is a sexually familial infection caused by a bacterium called Chlamydia trachomatis. It chiefly infects cells in the tubing which carrries piss from the vesica to the exterior of the organic structure, and besides the cervix of the womb. Chlamydia besides infects the cells in the rectum and eyes. Chlamydia is the figure one sexually familial disease in the United States, rates are highest in the West and Midwest. Missouri has a chlamydia rate that is much higher than the national norm. Health economic experts estimate that the chlamydial infections and the other jobs they cause cost Americans more than two billion dollars a twelvemonth. Over four million people become septic with chlamydia each twelvemonth. New instances of chlamydia are about four times more common than new instances of venereal herpes and venereal warts combined. Chlamydia is frequently dubbed the soundless epidemic because it is so prevailing, but so unheard of. Chlamydia is non every bit good known as other sexually familial diseases like gonorrhoea or pox. Chlamydia infection is greatest among immature grownups and adolescents, particularly in sexually active adult females less than twenty old ages of age. One of the grounds that chlamydia is so prevailing is because over 70 % of adult females who are infected don & apos ; t know they are infected because they lack marks or symptoms. About 50 % of work forces lack marks or symptoms. Chlamydia is transmitted in assorted ways. Chlamydia is chiefly transmitted through sexual intercourse. It is transferred during unwritten, vaginal, or anal sexual contact with an septic spouse. Chlamydia can besides be acquired in the throat from oral-genital contact. Chlamydia can besides be transferred from an septic female parent to her kid during bringing. The kids frequently have an oculus redness at birth or, in rarer instances pneumonia. There are several hazard factors for chlamydia. Prosecuting in insecure sex is a immense hazard factor for chlamydia. Having sex with more than one spouse besides increases the hazard of undertaking chlamydia. Being in a sexual relationship with person who has multiple sex spouses is besides a hazard factor in going infected with chlamydia. If symptoms do look, they normally appear from one hebdomad to one month after being infected. There are many symptoms that occur in work forces. Some include the redness of the urethra, a cutting feeling during micturition, mild, gluey, milklike, mucous secretion like discharge from the phallus, and possible itching around the gap. Others include hurting, or tenderness in the testiss. These symptoms may look to come and travel. Approximately half of work forces infected with chlamydia will ne'er hold these symptoms. Symptoms in adult females include mild, milklike, or mucus-like discharge, painful micturition, painful intercourse, shed blooding between periods, and abdominal hurting. Others include biting during micturition, and hurting caused by pelvic redness. Symptoms may besides look in the rectum, and can do discharge and hurting every bit good as diarrhoea. Chlamydia can besides do oculus infections, like pinkeye. Womans are less likely to demo symptoms with over 70 % of septic adult females demoing no symptoms at all. Babies that have been infected from birth show several symptoms. These symptoms include jobs take a breathing, redness of the oculus, premature birth, and even pneumonia. Chlamydia is easy treated if it is detected shortly after it is contracted. The most common manner of proving for chlamydia is for a physician to roll up a cell sample from the septic country, normally the neck or phallus, with a cotton swab. This sample is so sent to a research lab for rating and consequences. The most dependable ways to happen out whether the infection is chlamydial are through research lab trials. Normally, a physician or a nurse will direct a sample of Pus from the vagina or phallus to a research lab that will look for the bacterium. A referrel to a specializer GU clinic may besides be made so that extra testing can be done so a steadfast diagnosing can be made. Chlamydia can besides be tested for by taking a urine sample. This manner is less invasive, and less painful. The urine trial does non necessitate a pelvic test or mopping of the phallus. Consequences from the urine trial are available within 20 four hours. Chlamydia is frequently misdiagnosed as gonorrhoea because the symptoms of both diseases are so similar. Chlamydia and gonorrhoea are frequently contracted at the same clip. All sexually active adult females who are less than the age of 20, and those who have redness of the neck should be tested. Women less than age 20 four, who don & apos ; t utilize barrier preventives systematically, or have new or more than one sex spouse should be tested. Doctors recommend that since you can be infected and have no symptoms, it is of import to be tested if you have had more than one sex spouse, particularly if you are under the age of 20 five. It is possible to give the disease to person without even cognizing that you have it. That is why until a diagnosing is made, and intervention is administered, it is best to avoid any sexual contact. Chlamydia is easy treated with antibiotics such as Erythrocin, or tetracycline tablets. Common side effects of these interventions include diarrhoea, sickness, abdominal hurting, and purging. If chlamydia is left untreated it can do many long tirm side effects. The long term side effects of untreated chlamydia vary in work forces and adult females. The long term side effects that occur in work forces include epididymitis, which is an redness of the testiss that can do asepsis. Prostatitis is another side consequence that is caused by untreated chlamydia. Prostatitis is an infection of the prostate secretory organ. Reiter & apos ; s syndrome is an autoimmune, arthritis-like status that is besides caused by untreated chlamydia. Infertility is another side consequence that affects both work forces and adult females. In adult females the most terrible side consequence is Pelvic Inflammatory Disease. This is an go uping infection that spreads from the vagina and neck to the womb and fallopian tubing. This disease leads to asepsis. PID has symptoms including abdominal hurting, lower back hurting, hurting with intercourse, shed blooding between periods, and fever. Each twelvemonth up to one million adult females in the United

Chlamydia Essay, Research Paper Chlamydia

Sexually transmitted diseases infect 1000000s of people a twelvemonth. Some of the commonly known sexually transmitted diseases are herpes, syphillis, HIV, AIDS, venereal warts, and gonorrhoea. Some of these diseases are fatal, others can be cured with antibiotics. All of these are unsafe, but the most common sexually familial disease is a disease that isn’t every bit good known. This disease is called chlamydia. Chlamydia is a disease that is infecting immature grownups all over the state. This disease is of great concern for persons in high school and those in college. This disease is the taking cause of asepsis. Chlamydia is a sexually familial infection caused by a bacterium called Chlamydia trachomatis. It chiefly infects cells in the tubing which carrries piss from the vesica to the exterior of the organic structure, and besides the cervix of the womb. Chlamydia besides infects the cells in the rectum and eyes. Chlamydia is the figure one sexually familial disease in the United States, rates are highest in the West and Midwest. Missouri has a chlamydia rate that is much higher than the national norm. Health economic experts estimate that the chlamydial infections and the other jobs they cause cost Americans more than two billion dollars a twelvemonth. Over four million people become septic with chlamydia each twelvemonth. New instances of chlamydia are about four times more common than new instances of venereal herpes and venereal warts combined. Chlamydia is frequently dubbed the “silent epidemic” because it is so prevailing, but so unheard of. Chlamydia is non every bit good known as other sexually familial diseases like gonorrhoea or pox. Chlamydia infection is greatest among immature grownups and adolescents, particularly in sexually active adult females less than twenty old ages of age. One of the grounds that chlamydia is so prevailing is because over 70 % of adult females who are infected don’t know they are infected because they lack marks or symptoms. About 50 % of work forces lack marks or symptoms. Chlamydia is transmitted in assorted ways.

Chlamydia is chiefly transmitted through sexual intercourse. It is transferred during unwritten, vaginal, or anal sexual contact with an septic spouse. Chlamydia can besides be acquired in the throat from oral-genital contact. Chlamydia can besides be transferred from an septic female parent to her kid during bringing. The kids frequently have an oculus redness at birth or, in rarer instances pneumonia. There are several hazard factors for chlamydia. Prosecuting in insecure sex is a immense hazard factor for chlamydia. Having sex with more than one spouse besides increases the hazard of undertaking chlamydia. Being in a sexual relationship with person who has multiple sex spouses is besides a hazard factor in going infected with chlamydia.

If symptoms do look, they normally appear from one hebdomad to one month after being infected. There are many symptoms that occur in work forces. Some include the redness of the urethra, a cutting feeling during micturition, mild, gluey, milklike, mucous secretion like discharge from the phallus, and possible itching around the gap. Others include hurting, or tenderness in the testiss. These symptoms may look to come and travel. Approximately half of work forces infected with chlamydia will ne'er hold these symptoms. Symptoms in adult females include mild, milklike, or mucus-like discharge, painful micturition, painful intercourse, shed blooding between periods, and abdominal hurting. Others include biting during micturition, and hurting caused by pelvic redness. Symptoms may besides look in the rectum, and can do discharge and hurting every bit good as diarrhoea. Chlamydia can besides do oculus infections, like pinkeye. Womans are less likely to demo symptoms with over 70 % of septic adult females demoing no symptoms at all. Babies that have been infected from birth show several symptoms. These symptoms include jobs take a breathing, redness of the oculus, premature birth, and even pneumonia. Chlamydia is easy treated if it is detected shortly after it is contracted.

The most common manner of proving for chlamydia is for a physician to roll up a cell sample from the septic country, normally the neck or phallus, with a cotton swab. This sample is so sent to a research lab for rating and consequences. The most dependable ways to happen out whether the infection is chlamydial are through research lab trials. Normally, a physician or a nurse will direct a sample of Pus from the vagina or phallus to a research lab that will look for the bacterium. A referrel to a specializer GU clinic may besides be made so that extra testing can be done so a steadfast diagnosing can be made. Chlamydia can besides be tested for by taking a urine sample. This manner is less invasive, and less painful. The urine trial does non necessitate a pelvic test or mopping of the phallus. Consequences from the urine trial are available within 20 four hours. Chlamydia is frequently misdiagnosed as gonorrhoea because the symptoms of both diseases are so similar. Chlamydia and gonorrhoea are frequently contracted at the same clip. All sexually active adult females who are less than the age of 20, and those who have redness of the neck should be tested. Women less than age 20 four, who don’t use barrier preventives systematically, or have new or more than one sex spouse should be tested. Doctors recommend that since you can be infected and have no symptoms, it is of import to be tested if you have had more than one sex spouse, particularly if you are under the age of 20 five. It is possible to give the disease to person without even cognizing that you have it. That is why until a diagnosing is made, and intervention is administered, it is best to avoid any sexual contact. Chlamydia is easy treated with antibiotics such as Erythrocin, or tetracycline tablets. Common side effects of these interventions include diarrhoea, sickness, abdominal hurting, and purging. If chlamydia is left untreated it can do many long tirm side effects.

The long term side effects of untreated chlamydia vary in work forces and adult females. The long term side effects that occur in work forces include epididymitis, which is an redness of the testiss that can do asepsis. Prostatitis is another side consequence that is caused by untreated chlamydia. Prostatitis is an infection of the prostate secretory organ. Reiter’s syndrome is an autoimmune, arthritis-like status that is besides caused by untreated chlamydia. Infertility is another side consequence that affects both work forces and adult females. In adult females the most terrible side consequence is Pelvic Inflammatory Disease. This is an go uping infection that spreads from the vagina and neck to the womb and fallopian tubing. This disease leads to asepsis. PID has symptoms including abdominal hurting, lower back hurting, hurting with intercourse, shed blooding between periods, and fever. Each twelvemonth up to one million adult females in the United States develop PID, and every bit many as half of those are due to untreated chlamydial infections. PID can do scarring of the fallopian tubings which can barricade the tubing and prevent fertilisation from taking topographic point. It is estimated that over one hundred 1000 adult females a twelvemonth become sterile because of this disease. Pelvic Inflammatory Disease can besides increase the hazard of ectopic gestation. Scaring may interfere with the transition of a fertilized egg to the fallopian tubing, this causes the egg to attach itself to the fallopian tubing. This is an ectopic gestation. Womans who have chlamydia that is untreated base on balls it on to their kids, and can do their kids to hold long term oculus harm. Conjunctivitis normally develops within the first 10 yearss of life in a neonate that has a female parent with untreated chlamydia. Conjunctivitis is an oculus infection that includes discharge and conceited palpebras. Pneumonia is another side consequence that the female parent passes on to the babe. This frequently develops within three to six hebdomads of birth. Due to these hazards to the newborn, many physicians recommend that all pregnant adult females get tested for chlamydial infection. Untreated chlamydia besides leads to an infection around the liver called Perihepatitis. Reiter’s syndrome besides occurs in adult females who leave chlamydia untreated. However, when treated in clip, chlamydia has no long term side effects.

To forestall undertaking chlamydia at all, several things can be done. Abstinence from unwritten, vaginal, and anal sex is the lone manner to be wholly protected from chlamydia. If prosecuting in sexual activity, utilizing rubbers during vaginal, anal, and unwritten intercourse is a good manner to assist forestall undertaking chlamydia. Although rubbers do non supply perfect protection, they do offer the best protection available. Having a monogamous relationship in which both spouses are faithful at all times besides helps lower the hazard of undertaking chlamydia. Restricting the figure of sexual spouses, and holding each spouse tested will assist forestall undertaking chlamydia. Regular check-ups are besides recommended for forestalling chlamydia. An of import portion of forestalling chlamydia is non going sexually adumbrate when imbibing intoxicant or making other drugs.

There is some research traveling on to happen better ways to handle, name, and prevent chlamydial infections. Scientists late completed sequencing the genome for C. trachomatis. This will give scientists of import information as they try to develop a safe and effectual vaccinum. Developing topical microbicides, readyings that can be inserted into the vagina to forestall infection, that are effectual and easy to utilize, is a major research focal point. The lone downside to developing a vaccinum for chlamydia is that it may increase the figure of people practising insecure sex. There are many organisations that can be contacted to have information on chlamydia. The CDC National Prevention Information Network, the CDC National STD hotline, and the American Social Health Association are merely a few organisations that offer information on chlamydia. There are besides many web sites that offer information on chlamydia and many other sexually transmitted diseases. Information is readily available for anyone who is concerned about their wellness.

Knowing that chlamydia is the figure one sexually familial disease in the state, particularly among high school and college pupils, it is of import to go familiar with the disease. It is more of import to happen the ways to forestall and protect against the disease. Chlamydia should be a concern for all teens and immature grownups across the state. This disease should be a concern for every pupil on campus. Chlamydia is the figure one sexually familial disease at Towson. This disease is so easy treated by antibiotics, that it is a shame so many people are populating with it. Although chlamydia is a disease that frequently shows no symptoms, it does transport long term effects. This is the soundless epidemic that is ramping across America. The lone manner to halt chlamydia from distributing so quickly is to go informed about the disease and its effects. Chlamydia is a concern for everyone who is sexually active.

Chlamydia

Most adult females with chlamydia ( and about half of work forces ) do non see symptoms. Since symptoms may non be present, the lone manner to cognize if a individual who may be at hazard is infected with chlamydia is to be tested. Annual proving for the infection is recommended for all sexually active adult females age 25 and under. Annual testing is besides recommended for adult females over age 25 who have hazard factors for chlamydia ( e.g. , those with new spouses and those with multiple sex spouses ) . Depending on exact hazard factors, some adult females may necessitate more frequent showing, and work forces who might be at hazard should besides speak with their health care suppliers to see if proving is recommended.

Хламидиоз

По статистике ежегодно хламидиозом в мире заболевает 100 млн человек , а число инфицированных хламидиями людей на всем земном шаре по самым скромным подсчётам достигает одного миллиарда . По данным ВОЗ и многочисленных отечественных и зарубежных исследователей , урогенитальный хламидиоз является одним из самых распространённых заболеваний , передаваемых половым путём , поэтому серьёзную проблему для современной венерологии представляет создание максимально эффективных средств лечения так называемых негонококковых воспалительных заболеваний органов мочеполовой системы .

По разным данным , от 5 до 15 % молодых сексуально активных людей поражены хламидийной инфекцией . У пациентов дерматовенерологических диспансеров Российской Федерации данная инфекция встречается в 2—3 раза чаще , чем гонорея . Частота негонококковых воспалительных заболеваний органов мочеполовой системы в 5-6 раз превышает таковую у гонореи , их инкубационный период более длительный , клинические проявления менее выражены , чаще возникают осложнения , среди возбудителей преобладают хламидии . Широкое распространение хламидийной инфекции связано прежде всего с бессимптомным течением заболевания .

Этиология

Chlamydia trachomatis — представляют собой неподвижные , кокковидные , грамотрицательные облигатные внутриклеточные микроорганизмы . Хламидийная инфекция поражает главным образом мочеполовую систему . В настоящее время урогенитальный хламидиоз является самой распространённой ( до 60 % ) причиной негонококковых уретритов . Длительное время скрыто существуя , при неблагоприятных условиях ( воздействие антибиотиков , перегревание , переохлаждение , простуда ) хламидии способны трансформироваться в так называемые L-формы — как бы «впадают в спячку» . Данный феномен способствует длительному внутриклеточному паразитированию без конфликтов с иммунной системой хозяина . При делении клеток организма спящие хламидии передаются дочерним клеткам . Только в период иммуносупрессии ( подавления защитных сил ) возможно активное размножение и так называемая реверсия ( пробуждение ) хламидий из L-форм .

Патогенез

После прикрепления следует фагоцитоз элементарного тельца , им же и индуцируемый . Внутри клетки элементарные тельца существуют в цитоплазматической вакуоли — фагосоме , где хламидии остаются весь цикл роста , а поверхностные антигены микроба ингибируют распад и лизис фагосомы . Возможно , это одна из причин хронизации инфекции . Далее элементарное тельце преобразуется в ретикулярное тельце , уже метаболически активное и способное к делению . Ретикулярное тельце неинфекционно и не может выжить вне клетки . Ретикулярные тельца делятся 8-24 часа , конденсируются и превращаются в новые элементарные тельца . Через 48-72 часа клетка разрушается и элементарные тельца выделяются во внешнюю среду . Этим начинается новый цикл размножения хламидии , который длится около 48 часов .

Клинические проявления

У мужчин симптомы наличия хламидийной инфекции проявляются вначале , в большинстве случаев , как легкое воспаление мочеиспускательного канала затяжного ( хронического ) течения — уретрит , который продолжается не менее нескольких месяцев . У мужчин могут появиться скудные стекловидные выделения из мочеиспускательного канала . При мочеиспускании могут отмечаться зуд и жжение . Могут быть разные боли , в основном несильные : болеть может в мочеиспускательном канале , в мошонке , в пояснице , в яичках . Может повыситься температура — до 37 градусов , мужчина может ощущать общую слабость — следствие интоксикации . Может наблюдаться помутнение мочи , наличие в ней гнойных нитей . У некоторых мужчин могут даже появляться кровянистые выделения в конце мочеиспускания или при семяизвержении .

Слизь имеет белый цвет и похожа на налет пастообразного типа . Миндалины и задняя стенка горла начинают опухать . Если немного нажать на мягкие ткани в ротовой полости , то пациент испытывает болевые ощущения , но они кратковременные . Гиперемии не наблюдается . Гнойных отложений не возникает . Постепенно пациент теряет чувствительность рецепторов языка из-за специфического налета . Потом ему будет очень трудно жевать и глотать еду из-за боли при прикосновении и отечности . Слизь скапливается и под корнем языка . Пациент будет ощущать , будто во рту и трахее у него множество ссадин , которые побаливают . Эпителиальные слои языка постепенно будут высыхать , трескаться и шелушиться . Дыхание станет иметь очень неприятный запах . В некоторых случаях возникает непроизвольное шевеление и подергивание языка , которое вызывается спазмами .

Лечение

Поскольку Chlamydia trachomatis — внутриклеточный паразит , выбор препаратов ограничивается теми , которые способны проникать внутрь клетки . К макролидам относятся антибиотики , содержащие в молекуле макроциклическое лактановое кольцо , связанное с одним или несколькими углеводными остатками . Различия в химической структуре макролидов не столь существенны , но их физико-химические и биологические качества различаются . 14-членные макролиды — эритромицин , олеандомицин , кларитромицин , рокситромицин ; 15- членный — азитромицин ; 16-членные — джозамицин и спирамицин . Макролиды «нового поколения» незначительно отличаются от эритромицина по спектру действия , но имеют неполную перекрестную устойчивость с ним , улучшенную фармакокинетику и повышенный профиль безопасности .

Препаратом выбора в лечении урогенитального хламидиоза по последним международным стандартам ( рекомендации ВОЗ , Европейские рекомендации 2010 г . — European guideline for the direction of Chlamydia trachomatis infections ) является азитромицин — однократный прием соответствующей дозы ; либо применяется 7-дневный курс доксициклина . Альтернативными являются прочие макролиды , фторхинолоны . Профиль безопасности позволяет применять азитромицин при лечении беременных ( категория В по FDA ) . Для прочих макролидов недостаточно доказательных данных ( С-категория , либо не установлен уровень безопасности по FDA ) , чтобы можно было их рекомендовать при беременности .

What is chlamydia?

Chlamydia is the most normally reported sexually transmitted disease ( STD ) in the U.S. It is an infection with the bacteriums known as Chlamydia trachomatis. Chlamydia is really similar to gonorrhea in its symptoms and form of transmittal. It is of import to observe that many people ( both adult females and work forces ) who are infected with chlamydia do non hold any symptoms and may non be cognizant that they have the infection. Chlamydia infection can do lasting harm to the fallopian tubing in a adult female and can take to future sterility and an addition hazard of ectopic gestation. Chlamydia infection during gestation besides increases a adult female 's hazard of preterm labour and of holding a babe with low birth weight.

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